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   MODERATE ALCOHOL CONSUMPTION – CONTROVERSY AND CONFUSION
PART I

 By David G. Schwartz, M.D

      

     We hear of studies showing the cardiovascular benefits of moderate alcohol consumption, yet a host of other health problems are caused by alcohol.  What is a person to believe?

     It can be very confusing to the consumer to hear cardiologists and many health newsletters (even in the alternative health field) recommending moderation in alcohol consumption.  Moderation is usually defined as 1-2 drinks/day, and often no caveats are given about its dangers.

     After extensive review of summaries of the many medical journal references and other publications, it appears that there needs to be a big question mark after this advice.  Would it really be poor advice to recommend total avoidance of drinking ethanol?

     What appear to be benefits of moderate alcohol consumption stem from many epidemiological, case control, and non-randomized prospective studies comparing moderate drinking population groups or individuals with non-drinkers.  Many of these studies show markedly decreased risk of coronary disease, myocardial infarction, cardiac deaths, and in some cases, decrease in total mortality.    One study showed slight decrease in total mortality with one drink per day.  New England Journal of Medicine Dec 11, 1994; 337:1705-1714.  One study showed decrease in gallbladder disease Hepatology 1998; 27:1492-1498.  Some also showed decrease in osteoporosis.

     This article questions the validity of the purported cardiovascular benefits of alcohol and questions its relevance in the face of many other health issues.

      When we speak of moderation, what is moderate drinking, and what is a drink?  Commonly 1-2 drinks a day is called moderation.  I drink is usually counted as a 12oz beer, a 6 oz wine, or 1 ½ oz of whiskey.  (Dr. John R. Lee, M.D., in What Your Doctor May Not Tell You About Menopause, p. 173.  A can of beer usually contains 13 grams of ethanol, a glass of wine about 11 grams, and a shot of whiskey 15gms.  Medical Tribune July 9, 1992:9.

     How much alcohol is needed for maximum benefit for the heart?  The literature appears confusing regarding that.  A Japanese study showed decreased risk for heart disease with 22-68 grams/day, which could be as much as 4-5 drinks per day.  American Journal of Epidemiologist 1998;147(1)59-65.  What a way to save the heart by being drunk every day!  Most studies show a benefit up to about 2 drinks a day, and usually beyond that, heart disease risk goes up.  Circulation December 1, 1996; 94(11)3023-3025.

     Here is where the picture gets fuzzy.  We don’t have a precisely standardized dose to recommend (which is necessary for a drug, whether prescription or non-prescription). Every drug has its (presumed) benefits at a certain dosage level, and its overdose level or danger zone.  Alcohol is a toxic drug and no one has defined precisely how much is the minimal amount needed for benefit nor the maximum benefit level, nor the minimum risk level in regard to cardiovascular disease, not to mention all the other health risks related to alcohol.

     The other missing piece in a responsible recommendation for taking a drug is to have sufficient randomized prospective (preferably double-blind placebo) controlled experiments.  What we have now in regard to alcohol is epidemiological, case controlled, or non-randomized prospective studies, which may be sufficient for recommendations for foods or nutritional supplements which are basically nontoxic; however, drugs require much more stringent scientific safety testing.  Alcohol in common parlance is spoken of often like a food, since it is commonly consumed with meals as a beverage like water or sodas, but it needs to be underscored that ethanol is not a food.

     This lack of adequate scientific evidence in regard to alcohol and heart disease could be considered enough by itself to discredit any public statement that alcohol even in moderation is beneficial for one’s health, or that it prevents death from heart disease, but there are other factors which further cast doubt on this approach.

     Some possible mechanisms by which alcohol could prevent heart attacks are raising HDL cholesterol, decreasing fibrinogen, decreasing platelet “stickiness” (by decreasing thromboxane A2), and increasing plasminogen.  Postgraduate Medicine April 1992;91(5)271-277, Journal of Nutritional Biochemistry Nov 1992;3:562-579.  Most of these actions are ant-clotting factors, which can be accomplished also by fish oil, ginkgo biloba, garlic, and other natural, less toxic supplements and foods.  This issue is also muddled by the benefits of the non-alcohol portion of red wine, rich in polyphenols and other antioxidants.  Red wine is included in many of the alcohol studies commonly quoted.  An HDL increase can be accomplished by exercise and other nutritional measures.

     Some of the platelet-inhibiting actions can be accomplished by aspirin, which, if introduced today, would probably be available only by prescription because of its toxic effects.  The other common “benefit” of alcohol, to relax the body, “kill” emotional pain, and reduce the feelings of anxiety (the real reason most people drink), may be similar to the reasons people take Valium, an addictive schedule 4 controlled substance, regulated by the DEA.  So would this be considered a safe recommendation to take a drug combination of Valium/aspirin (Vaspirin or Aspium?), without a prescription and without precise dosage recommendations?

     Regarding addictive substances, no one knows who is susceptible to addiction to a drug until he or she tries it out for a period of time, than it is too late to prevent it. There are approximately 18 million Americans addicted to alcohol.  Even if there were a precise dosage to recommend, how many people would drink that precise amount, especially considering that it is commonly used recreationally and socially, not as a medicine, and that the substance itself impairs one’s judgment about how much to drink?

     Regarding any drug that decreases feelings of anxiety and covers up emotional pain, how are people to make the necessary adjustments and changes in habits, choices, work, and attitudes when there is a constant cover-up and avoidance of feeling emotional pains? These are warning signals, valuable information given by the mind/body for improved health and growth, and in some instances, for much needed counseling.

     When giving health-related advice, why not take the high road of recommending the best way to maximize our well being instead of the low road of making the most short- term choices to get by with something second best?  People are often capable of accomplishing a lot more than they are given credit for.

     There are many stress-relieving activities like exercise, sleep, play, recreation, positive social interactions, meditation and prayer that accomplish relaxation with longer lasting benefits than the expedient “solution” that alcohol offers, with its resultant rebound anxiety and other “backlashes.”

     For health and well being, recommending things that enhance the spiritual aspect of life cannot be ignored, because we are whole persons, emotional, mental, and spiritual, in addition to coronary vessels and myocardial tissue.  Alcohol use has never been known to promote long-term spiritual growth, integrity, commitment, ethics, and other values that strengthen a culture or society.  More precisely, ingesting a mind-numbing substance can compete with and distract from experiencing the “intoxicating” appreciation of beauty, for being “drunk” with the love of God in worship, for being inspired by inner peace discovered in prayer and meditation.

     Lifestyle choices can boost longevity as well as extending quality of life, as shown by Dr. James Fries in his study at Stanford University which showed lengthened disease-free interval, resulting in “compression of morbidity” to a time near the end of life, cited in the British Medical Journal 2000, vol. 321, pp1149-51.  There is no such data regarding drugs and the quality life-years saved.  The same applies to the drug ethanol.  So far we have sketchy crude morbidity and mortality data.

     These are some of the arguments for careful skepticism about giving advice publicly about moderation in alcohol use.  Part II will go into more detail regarding other health risks associated with light to moderate drinking.


MODERATE ALCOHOL USE – CONFUSION AND CONTROVERSY – PART II

By David G. Schwartz, M.D.